MRI/MRS: Use of Isotopes in Hyperpolarization

MRI/MRS Use of Isotopes in Hyperpolarization: Biomedical Applications

The single greatest impediment to the use of nuclear magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) in vivo is its limited sensitivity . Hyperpolarization promises enhanced magnetic resonance, with signal amplification up to 200,000‐fold greater than we have today, this technology will detect attomoles to nanomoles of isotopically labeled specific disease markers in ...

ISOTEC® Stable Isotopes Products for MRI/MRS and PET Imaging

Comparison between MRS and DWI in MRI of breast cancer

Introduction: Breast cancer is the most common cancer in women and is the second leading cause of cancer death (after lung cancer) in people throughout the world. Today, MRI is being used because of the limitations of x-ray mammography to detect breast cancer. Non-contrast sequences were associated to CE sequences in a breast MRI protocol for the sake of appraising morphologic ...

Detection of Glioblastoma Multiforme Tumor in Magnetic Resonance Spectroscopy Based on Support Vector Machine

Introduction: The brain tumor is an abnormal growth of tissue in the brain, which is one of the most important challenges in neurology. Brain tumors have different types. Some brain tumors are benign and some brain tumors are cancerous and malignant. Glioblastoma Multiforme (GBM) is the most common and deadliest malignant brain tumor in adults. The average survival rate for peo...

Potential Clinical Roles for Metabolic Imaging with Hyperpolarized [1-13C]Pyruvate

Clinical oncology relies increasingly on biomedical imaging, with anatomical imaging, especially using CT and 1H-MRI, forming the mainstay of patient assessment, from diagnosis to treatment monitoring. However, the need for further improvements in specificity and sensitivity, coupled with imaging techniques that are reaching their limit of clinically attainable spatial resolution, has resulted ...